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P,P-二甲基膦酰乙酸叔丁酯_分子结构_CAS_62327-21-3)
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P,P-二甲基膦酰乙酸叔丁酯

产品号 79522 公司名称 Sigma Aldrich
CAS号 62327-21-3 公司网站 http://www.sigmaaldrich.com
分子式 C8H17O5P 电 话 1-800-521-8956
分子量 224.191341 传 真
纯 度 ≥97.0% (GC) 电子邮件
保 存 Chembase数据库ID: 152135

产品价格信息

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产品别名

标题
tert-Butyl P,P-dimethylphosphonoacetate
IUPAC标准名
tert-butyl 2-(dimethoxyphosphoryl)acetate
IUPAC传统名
tert-butyl 2-(dimethoxyphosphoryl)acetate
别名
tert-Butyl ((oxo)dimethoxyphosphino)acetate
Dimethyl (tert-butoxycarbonyl)methylphosphonate
tert-Butyl (dimethoxyphosphinyl)acetate
(叔丁氧羰基)甲基膦酸二甲酯

产品登记号

PubChem SID 24887464
Beilstein号 4861886
CAS号 62327-21-3
MDL号 MFCD00042939

产品性质

纯度 ≥97.0% (GC)
线性分子式 (CH3O)2P(O)CH2COOC(CH3)3
沸点 86-87 °C/0.02 mmHg(lit.)
密度 1.131 g/mL at 20 °C(lit.)
闪点 110 °C
闪点 230 °F
折射率 n20/D 1.434
GHS危险品标识 GHS07
GHS警示词 Warning
GHS危险声明 H315-H319-H335
欧盟危险性物质标志 刺激性(Irritant) 刺激性(Irritant) (Xi)
MSDS下载 下载链接
个人保护装置 Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
GHS警示性声明 P261-P305 + P351 + P338
危险公开号 36/37/38
安全公开号 26
德国WGK号 3

产品详细信息

详细说明 (English)
Other Notes
Horner-Wittig reagent giving preferentially (E)-α,β-unsat. esters which are mildly saponified with acid6,7,8. Synthesis of derivatives by reductive alkylation9
Packaging
25, 100 mL in glass bottle
Application
Reactant for:
• Preparation of phosphonate terminated PPH dendrimers as anti-HIV-1 agents1
• Preparation of monodehydro diketopiperazines from ketoacyl amino acid amides via acid-catalyzed cyclization2
• Preparation of α,β-unsaturated esters for use in the guanidine-catalyzed oxa-Michael addition3
• Preparation of myxopyronin B and desmethyl myxopyronin B analogs, with antibacterial activity and inhibitory activity against bacterial RNA polymerase4
• Allylation and subsequent ring-closing metathesis in presence of Grubbs′ catalyst or intramolecular rhodium-catalyzed cyclopropanation reactions5
详细说明 (简体中文)
Other Notes
Horner-Wittig 试剂,优先生成 (E)-α,β-不饱和酯,这种酯可与酸发生轻度皂化反应6,7,8。也可用于通过还原烷基化反应合成衍生物9
包装
25, 100 mL in glass bottle
Application
Reactant for:
• Preparation of phosphonate terminated PPH dendrimers as anti-HIV-1 agents1
• Preparation of monodehydro diketopiperazines from ketoacyl amino acid amides via acid-catalyzed cyclization2
• Preparation of α,β-unsaturated esters for use in the guanidine-catalyzed oxa-Michael addition3
• Preparation of myxopyronin B and desmethyl myxopyronin B analogs, with antibacterial activity and inhibitory activity against bacterial RNA polymerase4
• Allylation and subsequent ring-closing metathesis in presence of Grubbs′ catalyst or intramolecular rhodium-catalyzed cyclopropanation reactions5

参考文献