(R)-(+)-2-甲基-CBS-噁唑硼烷 溶液

• 产品号: 457698
• CAS号: 112022-83-0
• 分子式: C18H20BNO
• 分子量: 277.1685

产品别名

• 标题: (R)-(+)-2-Methyl-CBS-oxazaborolidine solution
• IUPAC标准名: (3aR)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole
• IUPAC传统名: (3aR)-1-methyl-3,3-diphenyl-tetrahydropyrrolo[1,2-c][1,3,2]oxazaborole
• 别名: (R)-1-甲基,3,3-二苯基-四氢-吡咯并(1,2-c)(1,3,2)噁唑硼烷; (R)-Tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole; α,α-Diphenyl-D-prolinolmethylboronic acid cyclamide ester; (R)-1-Methyl,3,3-diphenyl-tetrahydro-pyrrolo(1,2-c)(1,3,2)oxazaborole; (R)-四氢-1-甲基-3,3-二苯基-1H,3H-吡咯并[1,2-c][1,3,2]噁唑硼烷; (R)-3-甲基-CBS-氧杂硼啶

产品登记号

• PubChem SID: 24869385
• CAS号: 112022-83-0
• MDL号: MFCD00078440

产品性质

• 浓度: 1 M in toluene
• Empirical Formula (Hill Notation): C18H20BNO
• 沸点: 111 °C
• 密度: 0.95 g/mL at 25 °C
• 闪点: 4 °C
• 闪点: 39.2 °F
• GHS警示词: Danger
• GHS危险声明: H225-H304-H315-H336-H361d-H373
• 欧盟危险性物质标志: 易燃性(Flammable) (F)
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 个人保护装置: Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
• GHS警示性声明: P210-P261-P281-P301 + P310-P331
• RID/ADR: UN 1294 3/PG 2
• 危险公开号: 63-11-38-48/20-65-67
• 安全公开号: 16-36/37-62
• 保存温度: room temp
• 联合国危险货物等级: 3
• 联合国危险货物编号: 1294
• 联合国危险货物包装类别(PG): 2
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Packaging
25 mL in Sure/Seal™
5 mL in glass bottle
Physical form
Precipitate may form in storage, but does not affect product quality. Gently heat product to 80-90 °C under an inert atmosphere to redissolve solids.
Application
CBS Catalysts for Asymmetric Reduction and Asymmetric Synthesis
The CBS (Corey-Bakshi-Shibata) oxazaborolidine catalyst has been used in the asymmetric reduction of prochiral ketones. Other applications include the enantioselective synthesis of α-hydroxy acids, α-amino acids, C2 symmetrical ferrocenyl diols, and propargyl alcohols.Used in a desymmetrizing reduction leading to (S)-4-hydroxycyclohexenone.

详细说明 (简体中文)

包装
25 mL in Sure/Seal™
5 mL in glass bottle
Physical form
储存时可能形成沉淀，但不影响产品质量。在惰性气体环境下将产品缓慢加热至 80-90°C，使固体再溶解。
Application
CBS Catalysts for Asymmetric Reduction and Asymmetric Synthesis
CBS (Corey-Bakshi-Shibata) 噁唑硼烷催化剂已被用于前手性酮的非对称性还原。其他应用包括 α-羟基酸、α-氨基酸、C2 对称二茂铁二醇以及炔丙醇的对映选择性合成。 用于去对称化还原反应，生成 (S)-4-羟基环己酮。