偶氮二甲酸二叔丁酯

• 产品号: 135992
• CAS号: 870-50-8
• 分子式: C10H18N2O4
• 分子量: 230.26092
• 纯 度: 98%

产品别名

• 标题: Di-tert-butyl azodicarboxylate
• IUPAC标准名: N-{[(tert-butoxy)carbonyl]imino}(tert-butoxy)formamide
• IUPAC传统名: N-[(tert-butoxycarbonyl)imino](tert-butoxy)formamide
• 别名: NSC 109889; DBAD; Bis(1,1-dimethylethyl)azodicarboxylate; Di-tert-butyl azodiformate

产品登记号

• PubChem SID: 24848251
• CAS号: 870-50-8
• EC号: 212-796-9
• Beilstein号: 1911434
• MDL号: MFCD00015001

产品性质

• 线性分子式: (CH3)3COCON=NCOOC(CH3)3
• 纯度: 98%
• 熔点: 89-92 °C(lit.)
• GHS警示词: Warning
• GHS危险声明: H315-H319-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• GHS警示性声明: P261-P305 + P351 + P338
• 危险公开号: 36/37/38
• 安全公开号: 26-36
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Application
Reagent employed in the electrophilic amination of β-keto esters catalyzed by an axially chiral guanidine.8 Building block in an enantioselective synthesis of 3,6-dihyropyridazines employing organocatalysts such a L-proline or (S)-2-pyrrolidinyl tetrazole.9
Utilized in the asymmetric Friedel-Crafts amination via a chiral organocatalyst.
Reactant for:
• Preparation of hexapeptide key fragments via stereoselective selenocyclization/oxidative deselenylation or hydrazination/cyclization reactions1
• Asymmetric Michael addition reactions2
• Preparation of dipeptidyl peptidase IV dependent water-soluble prodrugs via Mitsunobu reaction3
• Synthesis of pyrroloisoquinoline template via stereoselective N-acyliminium-mediated cyclization and enolate amination for synthesis of peptidomimetic compounds4
• Barbier-type propargylation reactions5
• Synthesis of bacterial peptide deformylase (PDF) inhibitor fumimycin6
• Asymmetric amination of glycine Schiff bases7
Packaging
5, 25 g in glass bottle

详细说明 (简体中文)

Application
用于以轴向手性胍催化 β 酮酯亲电氨基化的试剂。8用作以 L-脯氨酸或 (S)-2-吡咯烷基四唑这类有机催化剂催化进行的 3,6-二氢哒嗪的对映选择性合成的结构单元。9
用于通过手性有机催化剂催化进行的非对称 Friedel-Crafts 胺化。
Reactant for:
• Preparation of hexapeptide key fragments via stereoselective selenocyclization/oxidative deselenylation or hydrazination/cyclization reactions1
• Asymmetric Michael addition reactions2
• Preparation of dipeptidyl peptidase IV dependent water-soluble prodrugs via Mitsunobu reaction3
• Synthesis of pyrroloisoquinoline template via stereoselective N-acyliminium-mediated cyclization and enolate amination for synthesis of peptidomimetic compounds4
• Barbier-type propargylation reactions5
• Synthesis of bacterial peptide deformylase (PDF) inhibitor fumimycin6
• Asymmetric amination of glycine Schiff bases7
包装
5, 25 g in glass bottle