哌啶醇氧化物

• 产品号: 176141
• CAS号: 2226-96-2
• 分子式: C9H18NO2
• 分子量: 172.24472
• 纯 度: 97%

产品别名

• 标题: 4-Hydroxy-TEMPO
• IUPAC标准名: ol
• IUPAC传统名: tyrosine(.)
• 别名: Tempol; 4-羟基-2,2,6,6-四甲基哌啶-1-氧自由基; 4-Hydroxy-2,2,6,6-tetramethylpiperidine 1-oxyl

产品登记号

• PubChem SID: 24850555
• EC号: 218-760-9
• Beilstein号: 1422990
• CAS号: 2226-96-2
• MDL号: MFCD00006478

产品性质

• Empirical Formula (Hill Notation): C9H18NO2
• 纯度: 97%
• 熔点: 69-71 °C(lit.)
• GHS警示词: Warning
• GHS危险声明: H302-H315-H319-H335
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• GHS警示性声明: P261-P305 + P351 + P338
• 危险公开号: 22-36/37/38
• RTECS编号: TN8991000
• 安全公开号: 26-36
• 保存温度: 2-8°C
• 德国WGK号: 1

产品详细信息

详细说明 (English)

Application
A fluorous-tagged TEMPO derivative was prepared from the derived TEMPO propargylic ether and subsequent "click" reaction with a fluorous azide. This TEMPO derivative proved to be a highly effective catalyst in the oxidation of alcohols with bleach.1
Spin label for studying biological compounds and polymers.
Spin label reagent used in the chatacterization of antagonist and agonist binding sites of NK1 receptor. Also used to measure reactive oxygen generation in heart muscle by electron spin resonance spectroscopy. Cells that overexpress CYP2E1 can be protected from arachidonic acid toxicity damage by TEMPOL.
Packaging
1, 5, 25 g in glass bottle

详细说明 (简体中文)

Application
可由衍生化 TEMPO 丙炔醚和随后与氟叠氮化物发生的"点击"反应制备氟标记的 TEMPO 衍生物。在用漂白剂氧化醇的反应中证明该 TEMPO 衍生物是高效催化剂。1
研究生物学化合物和聚合物的自旋标记物。
自旋标记试剂，用于鉴定 NK1 受体的拮抗剂和激动剂结合位点。也可用于电子自旋共振光谱法测定心肌中活性氧的生成。TEMPOL 可保护过量表达 CYP2E1 的细胞免受花生四烯酸的毒性损伤。
包装
1, 5, 25 g in glass bottle