Application
Benzyl substituted Meldrum′s acids, available via aldol condensation and reduction with triethylammonium formate,1 were used to form indanones upon hydrolysis, loss of CO2, and Friedel-Crafts cyclization with chlorosulfonic acid.2 Knoevenagel condensations between aldehydes and Meldrum′s acid are accelerated in ionic liquids.3
Used in an efficient synthesis of isofraxidin.
Packaging
10, 25, 100 g in glass bottle |