(S,S′,R,R′)-TangPhos

• 产品号: 650889
• CAS号: 470480-32-1
• 分子式: C16H32P2
• 分子量: 286.372802

产品别名

• 标题: (S,S′,R,R′)-TangPhos
• IUPAC标准名: (2R)-1-tert-butyl-2-[(2R)-1-tert-butylphospholan-2-yl]phospholane
• IUPAC传统名: (2R)-1-tert-butyl-2-[(2R)-1-tert-butylphospholan-2-yl]phospholane
• 别名: (1S,1S′,2R,2R′)-1,1′-Di-tert-butyl-(2,2′)-diphospholane; (1S,1S′,2R,2R′)-1,1′-二叔丁基-(2,2′)-二磷烷

产品登记号

• PubChem SID: 24883788
• CAS号: 470480-32-1

产品性质

• Empirical Formula (Hill Notation): C16H32P2
• 熔点: 60-65 °C
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Application
Highly efficient in rhodium-catalyzed hydrogenation of α-dehyroamino acids and α-arylenamides,6 β-(acylamino)acrylates,7 itaconic acids, and enol acetates.8 Also gives outstanding enantioselectivities in asymmetric hydroformylation reactions.9
Chiral Quest Phosphine Ligands for Asymmetric HydrogenationCatalytic ligand used in:
• Preparation of α-borono-substituted alkylarenes by asymmetric hydroboration of styrenes catalyzed by copper(I)1
• Enantioselective synthesis of spiroindane di-Me acetic acid via hydrogenation of spiroindane di-Me acetic acid catalyzed by Ru(II)2
• Asymmetric γ-addition of thiols to allenoates3
• Rhodium-catalyzed intermolecular enantioselective hydroacylation of alkynes to give alpha- and beta-substituted unsaturated ketones by kinetic resolution4
• Stereoselective preparation of β-amino nitriles via rhodium-catalyzed asymmetric hydrogenation of amino acrylonitriles5
Packaging
100, 500 mg in glass bottle

详细说明 (简体中文)

Application
在 α-脱氢氨基酸、α-芳基烯酰胺、6β-(酰胺基)丙烯酸酯、7衣康酸以及乙酸烯醇酯的铑催化氢化中具有高效性。8也能在不对称加氢甲酰化反应中提供出色的对映选择性。9
Chiral Quest Phosphine Ligands for Asymmetric HydrogenationCatalytic ligand used in:
• Preparation of α-borono-substituted alkylarenes by asymmetric hydroboration of styrenes catalyzed by copper(I)1
• Enantioselective synthesis of spiroindane di-Me acetic acid via hydrogenation of spiroindane di-Me acetic acid catalyzed by Ru(II)2
• Asymmetric γ-addition of thiols to allenoates3
• Rhodium-catalyzed intermolecular enantioselective hydroacylation of alkynes to give alpha- and beta-substituted unsaturated ketones by kinetic resolution4
• Stereoselective preparation of β-amino nitriles via rhodium-catalyzed asymmetric hydrogenation of amino acrylonitriles5
包装
100, 500 mg in glass bottle