L-氨甲喋呤 水合物

• 产品号: 223948
• CAS号: 133073-73-1
• 分子式: C20H24N8O6
• 分子量: 472.45456
• 纯 度: 98%

产品别名

• 标题: L-Amethopterin hydrate
• IUPAC标准名: (2S)-2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}phenyl)formamido]pentanedioic acid hydrate
• IUPAC传统名: hydrate methotrexate
• 别名: 甲氨蝶呤 水合物; 氨甲叶酸 水合物; MTX 水合物; 4-Amino-10-methylfolic acid hydrate; L-4-Amino-N10-methylpteroylglutamic acid hydrate; L-Amethopterin hydrate; Antifolan hydrate; MTX hydrate; Methotrexate hydrate; Methylaminopterin hydrate; 对-[(2,4-二氨基喋啶-6)-N-甲基甲氨基]苯甲酰谷氨酸 水合物; L-氨甲喋呤 水合物; 氟安定 水合物; 氨甲喋呤 水合物

产品登记号

• PubChem SID: 24853414
• MDL号: MFCD00150847
• CAS号: 133073-73-1

产品性质

• Empirical Formula (Hill Notation): C20H22N8O5 · xH2O
• 纯度: 98%
• 相关基因信息: human ... DHFRP1(573971), FPGS(2356), SLC19A1(6573), TYMS(7298)mouse ... Dhfr(13361)rat ... Dhfr(24312)
• 比旋光度: [α]25/D +17°, c = 1 in 0.05 M Na2CO3
• GHS警示词: Danger
• GHS危险声明: H301-H315-H319-H360
• 欧盟危险性物质标志: 有毒(Toxic) (T)
• 个人保护装置: Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS警示性声明: P201-P301 + P310-P305 + P351 + P338-P308 + P313
• RID/ADR: UN 1544 6.1/PG 3
• 危险公开号: 61-25-36/38
• 安全公开号: 53-26-36/37-45
• 联合国危险货物等级: 6.1
• 联合国危险货物编号: 1544
• 联合国危险货物包装类别(PG): 3
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Packaging
100 mg in glass bottle
Application
Potent inhibitor of dihydrofolate reductase1 and agent for antitumor studies.2,3 Use to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also effective in treatment of pyrimethamine-resistant Plasmodium vivax malaria parasites.
Potent inhibitor of dihydrofolate reductase1 and agent for antitumor studies.2,3 Use to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also shows immunosuppressive effects in, e.g., rheumatoid arthritis.
Potent inhibitor of dihydrofolate reductase1 and agent for antitumor studies.2,3

详细说明 (简体中文)

包装
100 mg in glass bottle
Application
Potent inhibitor of dihydrofolate reductase1 and agent for antitumor studies.2,3 Use to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also effective in treatment of pyrimethamine-resistant Plasmodium vivax malaria parasites.
Potent inhibitor of dihydrofolate reductase1 and agent for antitumor studies.2,3 Use to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also shows immunosuppressive effects in, e.g., rheumatoid arthritis.
二氢叶酸还原酶的强效抑制剂1，以及用于抗癌抗菌素研究的试剂。2,3