光辉霉素 A 来源于褶皱链霉菌

• 产品号: 289930
• CAS号: 18378-89-7
• 分子式: C52H76O24
• 分子量: 1085.14544
• 纯 度: 90-95%

产品别名

• 标题: Mithramycin A from Streptomyces plicatus
• IUPAC标准名: (2S,3S)-3-[(1S,3S,4R)-3,4-dihydroxy-1-methoxy-2-oxopentyl]-2-{[(2S,4R,5R,6R)-4-{[(2S,4R,5R,6R)-4-{[(2S,4S,5R,6R)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy}-5-hydroxy-6-methyloxan-2-yl]oxy}-5-hydroxy-6-methyloxan-2-yl]oxy}-6-{[(2S,4R,5S,6R)-4-{[(2S,4R,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy}-5-hydroxy-6-methyloxan-2-yl]oxy}-8,9-dihydroxy-7-methyl-1,2,3,4-tetrahydroanthracen-1-one
• IUPAC传统名: (2S,3S)-3-[(1S,3S,4R)-3,4-dihydroxy-1-methoxy-2-oxopentyl]-2-{[(2S,4R,5R,6R)-4-{[(2S,4R,5R,6R)-4-{[(2S,4S,5R,6R)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy}-5-hydroxy-6-methyloxan-2-yl]oxy}-5-hydroxy-6-methyloxan-2-yl]oxy}-6-{[(2S,4R,5S,6R)-4-{[(2S,4R,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy}-5-hydroxy-6-methyloxan-2-yl]oxy}-8,9-dihydroxy-7-methyl-3,4-dihydro-2H-anthracen-1-one
• 别名: 普卡霉素; 金霉酸; Plicamycin; Aureolic acid

产品登记号

• Beilstein号: 5236667
• CAS号: 18378-89-7
• MDL号: MFCD00135618

产品性质

• Empirical Formula (Hill Notation): C52H76O24
• 纯度: 90-95%
• GHS警示词: Warning
• GHS危险声明: H302
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• 危险公开号: 22
• RTECS编号: PZ2800000
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Anticancer antibiotic. Inhibits transcription and protein synthesis. Binds to DNA in native chromatin. Substrate of Pgp in MDR phenotypes.

详细说明 (简体中文)

Biochem/physiol Actions
抗癌抗生素。抑制转录和蛋白质合成。与天然染色质中的 DNA 结合。MDR 表型的 Pgp 底物。