氟比洛芬

• 产品号: 447994
• CAS号: 5104-49-4
• 分子式: C15H13FO2
• 分子量: 244.2609232
• 纯 度: 97%

产品别名

• 标题: Flurbiprofen
• IUPAC标准名: 2-(3-fluoro-4-phenylphenyl)propanoic acid
• IUPAC传统名: flurbiprofen
• 别名: L-790,330; (±)-2-Fluoro-α-methyl-4-biphenylacetic acid; (±)-2-氟-α-甲基-4-联苯基乙酸

产品登记号

• MDL号: MFCD00079303
• EC号: 225-827-6
• CAS号: 5104-49-4

产品性质

• 线性分子式: C6H5C6H3(F)CH(CH3)CO2H
• 纯度: 97%
• 熔点: 110-112 °C(lit.)
• GHS警示词: Danger
• GHS危险声明: H301
• 欧盟危险性物质标志: 有毒(Toxic) (T)
• 个人保护装置: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• GHS警示性声明: P301 + P310
• RID/ADR: UN 2811 6.1/PG 3
• 危险公开号: 25
• RTECS编号: DU8341000
• 安全公开号: 36/37/39-45
• 联合国危险货物等级: 6.1
• 联合国危险货物编号: 2811
• 联合国危险货物包装类别(PG): 3
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Fluibiprofen is a cyclooxygenase (COX) inhibitor, which is an enzyme responsible for the conversion of arachidonic acid to prostaglandin G2 (PGG2) and PGG2 to prostaglandin H2 (PGH2) in the prostaglandin synthesis pathway. This decreases the prostaglandins which cause inflammation, pain, swelling and fever. Flurbiprofen inhibits the activity of both COX-1 and -2. The S enantiomer inhibits prostaglandin synthesis and has both anti-inflammatory and analgesic activity, while the R enantiomer does not inhibit prostaglandin synthesis and displays only analgesic activity.

详细说明 (简体中文)

Biochem/physiol Actions
Fluibiprofen is a cyclooxygenase (COX) inhibitor, which is an enzyme responsible for the conversion of arachidonic acid to prostaglandin G2 (PGG2) and PGG2 to prostaglandin H2 (PGH2) in the prostaglandin synthesis pathway. This decreases the prostaglandins which cause inflammation, pain, swelling and fever. Flurbiprofen inhibits the activity of both COX-1 and -2. The S enantiomer inhibits prostaglandin synthesis and has both anti-inflammatory and analgesic activity, while the R enantiomer does not inhibit prostaglandin synthesis and displays only analgesic activity.