Carbimazole

• 产品号: DB00389
• CAS号: 22232-54-8
• 分子式: C7H10N2O2S
• 分子量: 186.2315

产品别名

• 标题: Carbimazole
• IUPAC标准名: ethyl 3-methyl-2-sulfanylidene-2,3-dihydro-1H-imidazole-1-carboxylate
• IUPAC传统名: carbimazole
• 商标名: Atirozidina; Carbimazol Spofa; CG1; Neo-Thyreostat; Basolest; Carbotiroid; Mertiran; Neo-Mercazole; Neo-Tireol; Neomercazole; Tyrazol
• 别名: Athyromazole; Carbethoxymethimazole; Carbimazolum [INN-Latin]; Carbinazole; Carbimazol; Carbimazol [INN-Spanish, French]

产品登记号

• PubChem SID: 46506359
• PubChem CID: 31072
• CAS号: 22232-54-8

产品性质

• 疏水性(logP): 0.4

产品详细信息

详细说明 (English)

• Drug Groups: approved
• Description: An imidazole antithyroid agent. Carbimazole is metabolized to methimazole, which is responsible for the antithyroid activity. [PubChem]
• Indication: For the treatment of hyperthyroidism and thyrotoxicosis. It is also used to prepare patients for thyroidectomy.
• Pharmacology: Carbimazole is a carbethoxy derivative of methimazole. Its antithyroid action is due to its conversion to methimazole after absorption. It is used to treat hyperthyroidism and thyrotoxicosis.
• Affected Organisms: Humans and other mammals
• Protein Binding: 85%
• External Links: Wikipedia