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N-Acetyl-D-glucosamine

产品号 DB00141 公司名称 DrugBank
CAS号 7512-17-6 公司网站 http://www.ualberta.ca/
分子式 C8H15NO6 电 话 (780) 492-3111
分子量 221.2078 传 真
纯 度 电子邮件 david.wishart@ualberta.ca
保 存 Chembase数据库ID: 27

产品价格信息

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产品别名

标题
N-Acetyl-D-glucosamine
IUPAC标准名
N-[(3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide
IUPAC传统名
N-acetyl-D-glucosamine
商标名
Aflexa
Natures Blend Glucosamine
GS-500
Maxi GS
别名
2-Acetamido-2-deoxy-D-glucose
GlcNAc
Glucosamine Complex
N-Acetylchitosamine
NAG

产品登记号

CAS号 7512-17-6

产品性质

疏水性(logP) -2.1

产品详细信息

详细说明 (English)
Item Information
Drug Groups approved; nutraceutical
Description The N-acetyl derivative of glucosamine. [PubChem]
Indication For the treatment and prevention of osteoarthritis, by itself or in combination with chondroitin sulfate.
Toxicity Mouse, intravenous LD50 is 4170 mg/kg. Side effects that have been reported are mainly mild gastrointestinal complaints such as heartburn, epigastric distress and diarrhea. No allergic reactions have been reported including sulfa-allergic reactions to glucosamine sulfate.
Affected Organisms
Humans and other mammals
Biotransformation A significant fraction of ingested glucosamine is catabolized by first-pass metabolism in the liver.
Absorption Approximately 90% of orally administered glucosamine (salt form) gets absorbed from the small intestine.
External Links
PDRhealth

参考文献