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Riboflavin

产品号 DB00140 公司名称 DrugBank
CAS号 83-88-5 公司网站 http://www.ualberta.ca/
分子式 C17H20N4O6 电 话 (780) 492-3111
分子量 376.3639 传 真
纯 度 电子邮件 david.wishart@ualberta.ca
保 存 Chembase数据库ID: 26

产品价格信息

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产品别名

标题
Riboflavin
IUPAC标准名
7,8-dimethyl-10-[(2S,3S,4R)-2,3,4,5-tetrahydroxypentyl]-2H,3H,4H,10H-benzo[g]pteridine-2,4-dione
IUPAC传统名
riboflavin
商标名
Aqua-Flave
Beflavin
Beflavine
Bisulase
Dermadram
Fiboflavin
Flavaxin
Flavin
Flavin Bb
Flaxain
HSDB 817
Hyflavin
Hyre
Lactobene
Ovoflavin
Ribipca
Ribocrisina
Riboderm
Ribosyn
Ribotone
Ribovel
Vitaflavine
Vitasan B2
别名
Vitamin B2
Russupteridine Yellow III
Lactoflavine
Riboflavinum [INN-Latin]
Vitamin Bi
Riboflavina [INN-Spanish]
Vitamin G
Riboflavine [INN-French]
Lactoflavin

产品登记号

CAS号 83-88-5
PubChem CID 493570
PubChem SID 46507342

产品性质

疏水性(logP) -1.9
溶解度 84.7 mg/L

产品详细信息

详细说明 (English)
Item Information
Drug Groups approved; nutraceutical
Description Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. The richest natural source is yeast. It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and flavin-adenine dinucleotide. [PubChem]
Indication For the treatment of ariboflavinosis (vitamin B2 deficiency).
Pharmacology Riboflavin or vitamin B2 is an easily absorbed, water-soluble micronutrient with a key role in maintaining human health. Like the other B vitamins, it supports energy production by aiding in the metabolising of fats, carbohydrates, and proteins. Vitamin B2 is also required for red blood cell formation and respiration, antibody production, and for regulating human growth and reproduction. It is essential for healthy skin, nails, hair growth and general good health, including regulating thyroid activity. Riboflavin also helps in the prevention or treatment of many types of eye disorders, including some cases of cataracts.
Affected Organisms
Humans and other mammals
Biotransformation Hepatic.
Absorption Vitamin B2 is readily absorbed from the upper gastrointestinal tract.
Half Life 66-84 minutes
Protein Binding 60%
References
Zempleni J, Galloway JR, McCormick DB: Pharmacokinetics of orally and intravenously administered riboflavin in healthy humans. Am J Clin Nutr. 1996 Jan;63(1):54-66. [Pubmed]
External Links
Wikipedia
PDRhealth
Drugs.com

参考文献

  • Zempleni J, Galloway JR, McCormick DB: Pharmacokinetics of orally and intravenously administered riboflavin in healthy humans. Am J Clin Nutr. 1996 Jan;63(1):54-66. Pubmed