Cefsulodin sodium salt hydrate

• 产品号: C8145
• CAS号: 52152-93-9
• 分子式: C22H19N4NaO8S2
• 分子量: 554.52803

产品别名

• 标题: Cefsulodin sodium salt hydrate
• IUPAC标准名: sodium 4-carbamoyl-1-{[(6R,7R)-2-carboxylato-8-oxo-7-[(2R)-2-phenyl-2-sulfonatoacetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}pyridin-1-ium
• IUPAC传统名: sodium 4-carbamoyl-1-{[(6R,7R)-2-carboxylato-8-oxo-7-[(2R)-2-phenyl-2-sulfonatoacetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}pyridin-1-ium

产品登记号

• EC号: 257-692-4
• PubChem SID: 24278340
• CAS号: 52152-93-9
• MDL号: MFCD07793338

产品性质

• GHS警示词: Warning
• GHS危险声明: H315-H317-H319-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS警示性声明: P261-P280-P305 + P351 + P338
• 危险公开号: 36/37/38-42/43
• RTECS编号: UU1785000
• 安全公开号: 22-26-36/37-45
• 保存温度: 2-8°C
• 德国WGK号: 2

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Cefsulodin is a cephalosporin. Cephalosporins disrupt cell wall synthesis by inhibiting PBP crosslinking of peptidoglycan.
Application
Cefsulodin is a third generation cephalosporin antibiotic that has very specific activity against Pseudomonas aeruginosa. Cefuslodin is used in CIN (cefsulodin-Irgasan-novobiocin) agar to select for microorganisms such as E. coli. Cefsulodin is a substrate for rat Oatp1a4. It has been used to study multidrug resistance-associated protein 4 in efflux transport of prostaglandin E2 across the mouse blood-brain barrier1. Cefsulodin is used to study the effect of expression, binding, and inhibition of PBP1 and other penicillin-binding proteins (PBPs) on bacterial cell wall mucopeptide synthesis.
Cefsulodin is used to study the effect of expression, binding, and inhibition of PBP1 and other penicillin-binding proteins (PBPs) on bacterial cell wall mucopeptide synthesis.
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information