Acetazolamide

• 产品号: A6011
• CAS号: 59-66-5
• 分子式: C4H6N4O3S2
• 分子量: 222.24544
• 纯 度: ≥99%

产品别名

• 标题: Acetazolamide
• IUPAC标准名: N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide
• IUPAC传统名: acetazolamide
• 别名: N-(5-[Aminosulfonyl]-1,3,4-thiadiazol-2-yl)acetamide; 5-Acetamido-1,3,4-thiadiazole-2-sulfonamide; N-(5-Sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide

产品登记号

• PubChem SID: 24278144
• CAS号: 59-66-5
• EC号: 200-440-5
• MDL号: MFCD00003105

产品性质

• 纯度: ≥99%
• 相关基因信息: human ... CA1(759), CA12(771), CA14(23632), CA2(760), CA3(761), CA5A(763), CA5B(11238), CA9(768)mouse ... Car13(71934), Car5a(12352)rat ... Car2(54231), Car4(29242)
• pKa: 7.2
• 外观: powder
• 溶解度: 1 M NH4OH: soluble50 mg/mL
• 溶解度: DMSO: soluble
• 溶解度: methanol and ethanol: slightly soluble
• GHS警示词: Warning
• GHS危险声明: H315-H319
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• GHS警示性声明: P305 + P351 + P338
• 危险公开号: 36/38
• RTECS编号: AC8225000
• 安全公开号: 26
• 德国WGK号: 2

产品详细信息

详细说明 (English)

Application
Carbonic anhydrase inhibitor; increases cerebral blood flow.
Biochem/physiol Actions
Inhibits water permeability of membranes by interacting with aquaporins1,2
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. A6011.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.