5-Chloro-2′-deoxyuridine

• 产品号: C6891
• CAS号: 50-90-8
• 分子式: C9H11ClN2O5
• 分子量: 262.64704

产品别名

• 标题: 5-Chloro-2′-deoxyuridine
• IUPAC标准名: 5-chloro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
• IUPAC传统名: 5-chloro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-pyrimidine-2,4-dione
• 别名: CldU

产品登记号

• PubChem SID: 24892910
• MDL号: MFCD00006531
• CAS号: 50-90-8

产品性质

• GHS警示词: Warning
• GHS危险声明: H302-H312-H332-H351
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• GHS警示性声明: P280
• 危险公开号: 20/21/22-40
• RTECS编号: YU7400000
• 安全公开号: 36/37/39-45
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Application
5-Chloro-2′-deoxyuridine (CldU) is used as a thymidine analogue to study the miscoding potential of hypochlorous acid damage to DNA and DNA precursors. When used with antibody based immunofluorescent imaging, 5-Chloro-2′-deoxyuridine incorporation may be used in protocols to identify sites of DNA replication. CldU may be used as a labeling substrate in conjunction with other halogenated uridine labeling substrates such as bromodeoxyuridine (BrdU) and/or iododeoxyuridine (IdU).