Pipemidic acid

• 产品号: P7903
• CAS号: 51940-44-4
• 分子式: C14H17N5O3
• 分子量: 303.31648

产品别名

• 标题: Pipemidic acid
• IUPAC标准名: 8-ethyl-5-oxo-2-(piperazin-1-yl)-5H,8H-pyrido[2,3-d]pyrimidine-6-carboxylic acid
• IUPAC传统名: pipemidic acid
• 别名: 8-Ethyl-5,8-dihydro-5-oxo-2-(1-piperazinyl)pyrido(2,3-d)pyrimidine-6-carboxylic acid

产品登记号

• PubChem SID: 24898889
• CAS号: 51940-44-4
• MDL号: MFCD00057291
• EC号: 257-530-2

产品性质

• 德国WGK号: 2
• GHS警示词: Danger
• GHS危险声明: H317-H334
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS警示性声明: P261-P280-P342 + P311
• 危险公开号: 42/43
• 安全公开号: 22-36/37-45
• 相关基因信息: human ... CYP1A2(1544)

产品详细信息

详细说明 (English)

Application
Pipemidic acid is used to study DNA damage and mutagenic activity1. It has been used to induce articular lesions in the neonatal mouse2 and is used to study human lymphocyte blastogenesis and γ-interferon production 3.
Biochem/physiol Actions
Pipemidic acid modulates (inhibits) bacterial DNA gyrase-dependent processes such as DNA polymerization, (ATP-dependent) DNA supercoiling, and chromosome fragmentation. Pipemidic acid has been shown to induce inhibition of lymphocyte DNA synthesis3.
Pipemidic acid modulates (inhibits) bacterial DNA gyrase-dependent processes such as DNA polymerization, (ATP-dependent) DNA supercoiling, and chromosome fragmentation.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. P7903.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.