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Thiamphenicol
产品号	T0261	公司名称	Sigma Aldrich
CAS号	15318-45-3	公司网站	http://www.sigmaaldrich.com
分子式	C12H15Cl2NO5S	电话	1-800-521-8956
分子量	356.2222	传真
纯度		电子邮件
保存		Chembase数据库ID: 6228

产品价格信息

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产品别名

标题

Thiamphenicol

IUPAC标准名

2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-methanesulfonylphenyl)propan-2-yl]acetamide

IUPAC传统名

thiamphenicol

别名

D-threo-2,2-Dichloro-N-(β-hydroxy-α-[hydroxymethyl]-4-[methylsulfonyl]phenethyl)acetamide

产品登记号

CAS号	15318-45-3
MDL号	MFCD00467983
PubChem SID	24899874
Beilstein号	2819542
EC号	239-355-3

产品性质

个人保护装置	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RTECS编号	AB6680000
德国WGK号	2

产品详细信息

详细说明 (English)

Application
Thiamphenicol is an antibiotic that has been used to treat chancroid in men and uncomplicated gonorrhea1,2. It is used in studies of bacterial protein synthesis at the level of peptidyl transferase activity associated with the 23S rRNA of the 50S ribosomal subunit. It is used to study chloraniphenicol-thiamphenicol-resistance and the use of fluorinated analogs when resistance is encountered3.
Biochem/physiol Actions
Thiamphenicol inhibits mitochondrial protein synthesis of proteins such as cytochrome c oxidase.