Amastatin hydrochloride hydrate

• 产品号: A1276
• CAS号: 100938-10-1
• 分子式: C21H41ClN4O9
• 分子量: 529.02464
• 纯 度: ≥97% (HPLC)

产品别名

• 标题: Amastatin hydrochloride hydrate
• IUPAC标准名: (2S)-2-[(2S)-2-[(2S)-2-[(2S,3R)-3-amino-2-hydroxy-5-methylhexanamido]-3-methylbutanamido]-3-methylbutanamido]butanedioic acid hydrate hydrochloride
• IUPAC传统名: amastatin hydrate hydrochloride
• 别名: (2S,3R)-3-Amino-2-hydroxy-5-methylhexanoyl-Val-Val-Asp hydrochloride hydrate

产品登记号

• CAS号: 100938-10-1
• MDL号: MFCD00150636
• Beilstein号: 8888370
• PubChem SID: 24890521

产品性质

• 纯度: ≥97% (HPLC)
• 溶解度: methanol: soluble1 mM (Stock solution stable for 1 month at -20 °C. Working solution stable for 1 day.)
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
It inhibits cytosolic leucine aminopeptidase (EC.3.4.11.1), microsomal aminopeptidase M (EC.3.4.11.2) and bacterial leucine aminopeptidase (EC.3.4.11.10). It is less effective against aminopeptidase A (EC 3.4.11.7), the enzyme that converts angiotensin II to angiotensin III. Potentiates the CNS effects of vasopressin and oxytocin in vivo.1Effective concentration: 1-10 μM.
It inhibits cytosolic leucine aminopeptidase (EC.3.4.11.1), microsomal aminopeptidase M (EC.3.4.11.2) and bacterial leucine aminopeptidase (EC.3.4.11.10). It is less effective against aminopeptidase A (EC 3.4.11.7), the enzyme that converts angiotensin II to angiotensin III. Potentiates the CNS effects of vasopressin and oxytocin in vivo.1Effective concentration: 1-10 μM.