氨苄西林

• 产品号: A9393
• CAS号: 69-53-4
• 分子式: C16H19N3O4S
• 分子量: 349.40476
• 纯 度: 96.0-100.5% (anhydrous basis)

产品别名

• 标题: Ampicillin
• IUPAC标准名: (2S,5R,6R)-6-[(2R)-2-amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• IUPAC传统名: ampicillin
• 别名: 氨苄青霉素

产品登记号

• MDL号: MFCD00005175
• Beilstein号: 1090925
• PubChem SID: 24891442
• EC号: 200-709-7
• CAS号: 69-53-4

产品性质

• 纯度: 96.0-100.5% (anhydrous basis)
• 适用性: suitable for 1694 per US EPA
• 熔点: 208 °C (dec.)(lit.)
• 溶解度: 1 M NH4OH: soluble50 mg/mL
• GHS警示词: Danger
• GHS危险声明: H315-H317-H319-H334-H335
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS警示性声明: P261-P280-P305 + P351 + P338-P342 + P311
• 危险公开号: 36/37/38-42/43
• RTECS编号: XH8350000
• 安全公开号: 22-26-36/37
• 保存温度: 2-8°C
• 德国WGK号: 2

产品详细信息

详细说明 (English)

Frequently Asked Questions
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Biochem/physiol Actions
A β-lactam antibiotic with an amino group attached to the penicillin structure. Inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Bactericidal only to growing Escherichia coli. Mode of resistance: Cleavage of β-lactam ring of ampicillin by β-lactamase. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
Application
Ampicillin is used to select bacteria cells with specific resistance during general microbiology studies. It is used to study antibiotic resistance and penetration limitations, the synergy between multiple antibiotics, certain bloodstream infections, and has been used to develop PCR assays to detect resistance genes in cerebrospinal fluid 1,2,3,4.