Penicillin G sodium salt 钠盐

• 产品号: PENNA
• CAS号: 69-57-8
• 分子式: C16H17N2NaO4S
• 分子量: 356.37195

产品别名

• 标题: Penicillin G sodium salt
• IUPAC标准名: sodium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
• IUPAC传统名: sodium benzylpenicillin(1-)
• 别名: Benzylpenicillin sodium salt 钠盐

产品登记号

• PubChem SID: 24899068
• Beilstein号: 3834217
• CAS号: 69-57-8
• MDL号: MFCD00069666
• EC号: 200-710-2

产品性质

• GHS警示词: Danger
• GHS危险声明: H317-H334
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS警示性声明: P261-P280-P342 + P311
• 危险公开号: 42/43
• RTECS编号: XH9800000
• 安全公开号: 22-36/37-45
• 德国WGK号: 2

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Mode of Action: Inhibits bacterial cell wall synthesis.Antimicrobial spectrum: Gram-positive bacteria.
Penicillin G is active against gram-positive and gram-negative aerobic and anaerobic bacteria. Penicillin G inhibits cell wall synthesis by binding to penicillin binding proteins (PBPs), which inhibits peptidoglycan chain cross-linking. Penicillin G is stable against hydrolysis by β-lactamases, such as penicillinases and cephalosporinases.
Application
Penicillin G is narrow spectrum antibiotic. It is the drug of choice for Streptococcus pneumoniae, groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridans group streptococci, and non-penicillinase producing staphylococcus. Penicillin G sodium salt is used to study the diagnostic and therapeutic implications of gentamicin-resistant Enterococcus faecalis sequence type 6 with reduced penicillin susceptibility 1. It is used in cell culture alone as well as in combination with streptomcyin and other antibiotics2.
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information