S-(5′-Adenosyl)-L-methionine chloride dihydrochloride

• 产品号: A7007
• CAS号: 86867-01-8
• 分子式: C15H23ClN6O5S
• 分子量: 434.89832
• 纯 度: ≥80%

产品别名

• 标题: S-(5′-Adenosyl)-L-methionine chloride dihydrochloride
• IUPAC标准名: [(3S)-3-amino-3-carboxypropyl]({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl})methylsulfanium chloride
• IUPAC传统名: SAMe chloride
• 别名: AdoMet; SAM chloride dihydrochloride; Active methionine

产品登记号

• PubChem SID: 24891164
• CAS号: 86867-01-8
• EC号: 246-184-8
• Beilstein号: 6560002
• MDL号: MFCD22571809

产品性质

• 生物来源: from yeast (L-Methionine enriched)
• 纯度: ≥80%
• 运输包装: dry ice
• 溶解度: H2O: soluble100 mg/mL
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Analysis Note
Purity based on UV and HPLC.
Caution
This material is 80-90% pure when prepared, but is very unstable. As much as 10% purity loss per day at 25 °C has been noted.
Biochem/physiol Actions
Methyl donor; cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). Although present in all cells, it is concentrated in liver where 85% of all methylation reactions occur. It is also involved in regulating liver function, growth, and response to injury.