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红霉素_分子结构_CAS_114-07-8)
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红霉素

产品号 E5389 公司名称 Sigma Aldrich
CAS号 114-07-8 公司网站 http://www.sigmaaldrich.com
分子式 C37H67NO13 电 话 1-800-521-8956
分子量 733.92678 传 真
纯 度 电子邮件
保 存 Chembase数据库ID: 84

产品价格信息

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产品别名

标题
Erythromycin
IUPAC标准名
(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione
IUPAC传统名
erythromycin
别名
E-Mycin
Erythrocin

产品登记号

CAS号 114-07-8
EC号 204-040-1
MDL号 MFCD00084654
PubChem SID 24894612
Beilstein号 75279

产品性质

杂质 ≤0.1 EU/mg endotoxin
药效 ≥850 μg per mg
适用性 suitable for cell culture
相关基因信息 human ... ABCB1(5243), CYP3A4(1576), MLNR(2862)mouse ... Abcb1a(18671), Abcb1b(18669)
外观 powder
溶解度 2 M HCl: soluble50 mg/mL (Stock solutions should be stored at 2-8 °C. Stable at 37 °C for 3 days.)
溶解度 ethanol: soluble (Stock solutions should be stored at 2-8 °C. Stable at 37 °C for 3 days.)
个人保护装置 Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RTECS编号 KF437500
德国WGK号 3

产品详细信息

详细说明 (English)
Application
Recommended for use in cell culture applications at 100 mg/L
Biochem/physiol Actions
Inhibits protein synthesis (elongation) at the level of transpeptidation (aminoacyl translocation A-site to P-site).
Mode of Action: Inhibits elongation at transpeptidation step.Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
Other Notes
Macrolide antibiotic.
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information

参考文献