孕酮

• 产品号: P8783
• CAS号: 57-83-0
• 分子式: C21H30O2
• 分子量: 314.4617

产品别名

• 标题: Progesterone
• IUPAC标准名: (1S,2R,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-6-en-5-one
• IUPAC传统名: progesterone
• 别名: 孕烯二酮

产品登记号

• PubChem SID: 24898978
• MDL号: MFCD00003658
• CAS号: 57-83-0
• EC号: 200-350-6
• Beilstein号: 1915950

产品性质

• 简要说明: synthesized from materials derived from plant source
• 药效: 0.1-20 ng/mL
• 适用性: suitable for cell culture
• 相关基因信息: human ... ABCB1(5243), AR(367), CYP2C9(1559), EBP(10682), ESR1(2099), ESR2(2100), NR3C1(2908), NR3C2(4306), PGR(5241), SERPINA6(866)mouse ... Esr1(13982)rat ... Ar(24208), Nr3c1(24413), Pgr(25154)
• 外观: powder
• 熔点: 128-132 °C(lit.)
• 溶解度: absolute ethanol: soluble1 mg/mL
• GHS警示词: Warning
• GHS危险声明: H351
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 个人保护装置: Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS警示性声明: P281
• 危险公开号: 40
• RTECS编号: TW0175000
• 安全公开号: 36/37
• 德国WGK号: 3

产品详细信息

详细说明 (简体中文)

Application
Use in cell culture applications to study sterol regulation of cell signaling and gene expression.
Other Notes
由卵巢黄体产生的类固醇激素。
Reconstitution
To prepare 20μg/ml stock solution, add 1ml absolute ethanol per mg progesterone, gently swirl to dissolve, add 49ml sterile medium per ml ethanol.
Physical form
powder-RT; stock-frozen in working aliquots, avoid repeated freeze/thaw
Biochem/physiol Actions
诱导子宫内皮细胞的成熟和分泌活动;抑制排卵。孕酮与乳腺癌的病因有关。