利福平

• 产品号: R3501
• CAS号: 13292-46-1
• 分子式: C43H58N4O12
• 分子量: 822.94022
• 纯 度: ≥97% (HPLC)

产品别名

• 标题: Rifampicin
• IUPAC标准名: (7S,9Z,11S,12R,13S,14R,15R,16R,17S,18S,19Z,21Z)-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-26-[(E)-N-(4-methylpiperazin-1-yl)carboximidoyl]-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.1^4,^7.0^5,^2^8]triaconta-1(29),2,4,9,19,21,25,27-octaen-13-yl acetate
• IUPAC传统名: (7S,9Z,11S,12R,13S,14R,15R,16R,17S,18S,19Z,21Z)-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-26-[(E)-N-(4-methylpiperazin-1-yl)carboximidoyl]-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.1^4,^7.0^5,^2^8]triaconta-1(29),2,4,9,19,21,25,27-octaen-13-yl acetate
• 别名: 利米定; 甲哌利福霉素; 3-(4-甲基-1-哌嗪基亚胺甲基)利福霉素SV

产品登记号

• PubChem SID: 24899363
• EC号: 236-312-0
• CAS号: 13292-46-1
• Beilstein号: 5723476
• MDL号: MFCD00151389

产品性质

• 纯度: ≥97% (HPLC)
• 外观: faint-orange to red-brown powder
• 溶解度: H2O: soluble1.3 mg/mL (pH 4.3)
• 溶解度: DMSO: soluble100 mg/mL
• 溶解度: H2O: soluble2.5 mg/mL at 25 °C (pH 7.3)
• GHS警示词: Warning
• GHS危险声明: H302-H315-H319-H335
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• GHS警示性声明: P261-P305 + P351 + P338
• 危险公开号: 22-36/37/38
• RTECS编号: VJ7000000
• 安全公开号: 26-36
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Biochem/physiol Actions
Inhibits the assembly of DNA and protein into mature virus particles.
Mode of Action: Inhibits initiation of RNA synthesis by binding to β-subunit of RNA polymerase.
Rifampicin inhibits the assembly of DNA and protein into mature virus particles. It inhibits initiation of RNA synthesis by binding to β-subunit of RNA polymerase, which results in cell death1.
Application
Rifampicin is used to treat Tuberculosis and Tuberculosis-related mycobacterial infections1. It is widely used as an antipruritic agent in the autoimmune cholestatic liver disease, primary biliary cirrhosis (PBC). It has been shown to cause hepatitis2.
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information