Sp-Adenosine 3′,5′-cyclic monophosphorothioate triethylammonium salt hydrate

• 产品号: A166
• CAS号: 93602-66-5(anhydrous)
• 分子式: C16H27N6O5PS
• 分子量: 446.461541
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: Sp-Adenosine 3′,5′-cyclic monophosphorothioate triethylammonium salt hydrate
• IUPAC标准名: (2S,4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)-7-hydroxy-2-sulfanyl-hexahydro-1,3,5,2λ^5-furo[3,2-d][1,3,2λ^5]dioxaphosphinin-2-one; triethylamine
• IUPAC传统名: (2S,4aR,6R,7R,7aS)-6-(6-aminopurin-9-yl)-7-hydroxy-2-sulfanyl-tetrahydro-4H-1,3,5,2λ^5-furo[3,2-d][1,3,2λ^5]dioxaphosphinin-2-one; triethylamine
• 别名: Sp-cAMPS triethylammonium salt; Sp-Cyclic 3′,5′-hydrogen phosphorothioate adenosine hydrate

产品登记号

• CAS号: 93602-66-5(anhydrous)
• MDL号: MFCD01459901
• PubChem SID: 24890576

产品性质

• 纯度: ≥98% (HPLC)
• 外观: white solid
• 比旋光度: [α]22/D -25.43°, c = 0.99 in H2O(lit.)
• 溶解度: H2O: soluble
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Sp-Diastereomer of adenosine 3′,5′-cyclic monophosphorothioate is a potent, membrane-permeable activator of cAMP dependent protein kinase I and II that mimics the effects of cAMP as a second messenger in numerous systems while being resistant to cyclic nucleotide phosphodiesterases; exhibits greater specificity and affinity than forskolin and cAMP analogs such as dibutyryl-cAMP.