N-Acetyl-L-tryptophan 3,5-bis(trifluoromethyl)benzyl ester

• 产品号: A5330
• CAS号: 148451-96-1
• 分子式: C22H18F6N2O3
• 分子量: 472.3803392
• 纯 度: ≥99% (TLC)

产品别名

• 标题: N-Acetyl-L-tryptophan 3,5-bis(trifluoromethyl)benzyl ester
• IUPAC标准名: [3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-acetamido-3-(1H-indol-3-yl)propanoate
• IUPAC传统名: [3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-acetamido-3-(1H-indol-3-yl)propanoate
• 别名: L-732,138

产品登记号

• CAS号: 148451-96-1
• MDL号: MFCD00237267
• PubChem SID: 24277690

产品性质

• 纯度: ≥99% (TLC)
• 相关基因信息: human ... TACR1(6869)
• 外观: powder
• 熔点: 147-148 °C(lit.)
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 保存温度: -20°C

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Competitive substance P receptor antagonist. It is approximately 1000-fold more potent at cloned human NK-1 receptors than at cloned human NK-2 and NK-3 receptors; and approximately 200-fold more potent at human NK-1 receptors than at rat NK-1 receptors. The IC50 for the human NK-1 receptor expressed in CHO cells is approximately 2 nM.