4-Chlorouracil

• 产品号: C9525
• CAS号: 4270-27-3
• 分子式: C4H3ClN2O2
• 分子量: 146.53182
• 纯 度: ≥99%

产品别名

• 标题: 4-Chlorouracil
• IUPAC标准名: 6-chloro-1,2,3,4-tetrahydropyrimidine-2,4-dione
• IUPAC传统名: 6-chloro-1,3-dihydropyrimidine-2,4-dione
• 别名: 6-Chlorouracil; 6-Chloro-2,4-dihydroxypyrimidine; 4-Chloro-2,6-dihydroxypyrimidine

产品登记号

• CAS号: 4270-27-3
• PubChem SID: 24893168
• EC号: 224-258-0
• MDL号: MFCD00014595

产品性质

• 纯度: ≥99%
• GHS警示词: Warning
• GHS危险声明: H315-H319-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• GHS警示性声明: P261-P305 + P351 + P338
• 危险公开号: 36/37/38
• 安全公开号: 26-36
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Application
Chlorouracil (4-Chlorouracil; 6-Chlorouracil) is a halogenated uracil that is useful in studies of the effects of halogenation on nucleic acid base-pair stability and alkali metal ion affinity.Reaction of 6-chlorouracil with 4-(dimethylamino)pyridine, 4-methylpyridine, and pyridin-4-yl-morpholine yielded pyridinium-substituted uracils as chlorides which were converted into pyridinium uracilates by deprotonation. These heterocyclic mesomeric betaines are cross-conjugated and thus possess separate cationic (pyridinium) and anionic (uracilate) moieties. Calculations and X-ray single crystal analyses may be used to characterize these systems and to compare the salts with the betaines.