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Limonin

产品号 L9647 公司名称 Sigma Aldrich
CAS号 1180-71-8 公司网站 http://www.sigmaaldrich.com
分子式 C26H30O8 电 话 1-800-521-8956
分子量 470.5116 传 真
纯 度 >90% (HPLC) 电子邮件
保 存 Chembase数据库ID: 72956

产品价格信息

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产品别名

标题
Limonin
IUPAC标准名
(1R,2R,7S,10R,13R,14R,16S,19R,20S)-19-(furan-3-yl)-9,9,13,20-tetramethyl-4,8,15,18-tetraoxahexacyclo[11.9.0.02,7.02,10.014,16.014,20]docosane-5,12,17-trione
IUPAC传统名
limonin
别名
Limonoic acid 3,19:16,17 dilactone

产品登记号

CAS号 1180-71-8
PubChem SID 24896458
MDL号 MFCD00075922

产品性质

生物来源 from citrus seeds
纯度 >90% (HPLC)
保存温度 2-8°C
德国WGK号 3

产品详细信息

详细说明 (English)
Biochem/physiol Actions
Limonin is a triterpenoid aglycone that is a bitter principle of citrus fruits. It has anti-proliferative, proapoptotic activity on several cancer cell lines and inhibits azoxymethane-induced colon cancer in rats. It also inhibits HIV-1 replication in culturedf monocytes, macrophages, and mononuclear cells, perhaps by inhibition of HIV-1 protease activity.
General description
Limonin may be used in assays to quantify limonin in citrus products. It may also be used in other assays as a control, standard, or competitor or in studies on the physiology, metabolism, and biosynthesis of limonin.

参考文献