8-(4-Chlorophenylthio)-guanosine 3′,5′-cyclic monophosphorothioate, Rp Isomer triethylammonium salt

• 产品号: C240
• CAS号: 276696-61-8
• 分子式: C22H30ClN6O6PS2
• 分子量: 605.066961
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: 8-(4-Chlorophenylthio)-guanosine 3′,5′-cyclic monophosphorothioate, Rp Isomer triethylammonium salt
• IUPAC标准名: 9-[(2R,4aR,6R,7R,7aS)-2,7-dihydroxy-2-sulfanylidene-hexahydro-1,3,5,2λ^5-furo[3,2-d][1,3,2λ^5]dioxaphosphinin-6-yl]-2-amino-8-[(4-chlorophenyl)sulfanyl]-6,9-dihydro-1H-purin-6-one; triethylamine
• IUPAC传统名: 9-[(2R,4aR,6R,7R,7aS)-2,7-dihydroxy-2-sulfanylidene-tetrahydro-4H-1,3,5,2λ^5-furo[3,2-d][1,3,2λ^5]dioxaphosphinin-6-yl]-2-amino-8-[(4-chlorophenyl)sulfanyl]-1H-purin-6-one; triethylamine
• 别名: Rp-8-[(4-Chlorophenyl)thio]-guanosine-cyclic 3′,5′-hydrogen phosphorothioate triethylammonium salt; Rp-8-CPT-cGMPS; Rp-8-[(4-Chlorophenyl)thio]-cGMPS triethylammonium salt

产品登记号

• CAS号: 276696-61-8
• MDL号: MFCD04037247

产品性质

• 纯度: ≥98% (HPLC)
• 外观: white solid
• 溶解度: H2O: soluble5 mg/mL
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Rp-8-CPT-cGMP is a potent inhibitor of protein kinase G Ia, Ib, and type II.
Linkage
8-(4-Chlorophenylthio)-guanosine 3′,5′-cyclic monophosphorothioate, Rp Isomer triethylammonium salt is more cell permeable than Rp-cGMPS triethylamine.