4-(N-马来酰亚胺基甲基)环己烷-1-羧酸琥珀酰亚胺酯

• 产品号: M5525
• CAS号: 64987-85-5
• 分子式: C16H18N2O6
• 分子量: 334.32392
• 纯 度: ≥98%

产品别名

• 标题: 4-(N-Maleimidomethyl)cyclohexanecarboxylic acid N-hydroxysuccinimide ester
• IUPAC标准名: 2,5-dioxopyrrolidin-1-yl 4-[(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl]cyclohexane-1-carboxylate
• IUPAC传统名: SMCC
• 别名: SMCC; N-琥珀酰亚胺基4-(马来酰亚胺基甲基)环己烷羧酸酯

产品登记号

• CAS号: 64987-85-5
• PubChem SID: 24897020
• Beilstein号: 1555271
• MDL号: MFCD00009634

产品性质

• 纯度: ≥98%
• 运输包装: wet ice
• 外观: powder
• 熔点: 180-182 °C(lit.)
• 溶解度: chloroform: soluble50 mg/mL
• 溶解度: DMF: soluble
• GHS警示词: Warning
• GHS危险声明: H315-H319-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• GHS警示性声明: P261-P305 + P351 + P338
• 危险公开号: 36/37/38
• 安全公开号: 26-36
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Application
A heterobifunctional cross-linking reagent incorporating an extended spacer with amine and sulfhydryl reactivity. Typically coupled initially to molecules containing primary amine by amide bond buffered at pH 7.5 (6.5-8.5). The second coupling is specific for molecules containing free sulfhydryl by thioether linkage buffered at pH 6.8 (6.5-7.0). Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates. Contains 9 atom linker. An extended aliphatic spacer stabilizes the maleimide prior to coupling compared to aromatic spacers.