N2,2′-O-Dibutyrylguanosine 3′,5′-cyclic monophosphate sodium salt hydrate_分子结构_CAS_51116-00-8)

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N2,2′-O-Dibutyrylguanosine 3′,5′-cyclic monophosphate sodium salt hydrate
产品号	D3510	公司名称	Sigma Aldrich
CAS号	51116-00-8	公司网站	http://www.sigmaaldrich.com
分子式	C18H24N5NaO9P	电话	1-800-521-8956
分子量	508.374791	传真
纯度	≥95% (HPLC)	电子邮件
保存		Chembase数据库ID: 133692

产品价格信息

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产品别名

标题

N2,2′-O-Dibutyrylguanosine 3′,5′-cyclic monophosphate sodium salt hydrate

IUPAC标准名

6-(2-butanamido-6-oxo-6,9-dihydro-3H-purin-9-yl)-2-hydroxy-2-oxo-hexahydro-1,3,5,2λ⁵-furo[3,2-d][1,3,2λ⁵]dioxaphosphinin-7-yl butanoate sodium

IUPAC传统名

6-(2-butanamido-6-oxo-3H-purin-9-yl)-2-hydroxy-2-oxo-tetrahydro-4H-1,3,5,2λ⁵-furo[3,2-d][1,3,2λ⁵]dioxaphosphinin-7-yl butanoate sodium

产品登记号

CAS号	51116-00-8
MDL号	MFCD00038422
PubChem SID	24893759
EC号	256-992-2

产品性质

纯度	≥95% (HPLC)
外观	off-white powder
溶解度	H2O: soluble50 mg/mL
个人保护装置	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
保存温度	-20°C
德国WGK号	3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Cell permeable, cGMP analog that activates protein kinase G. Has been shown to increase intracellular calcium concentration in neurons and hepatocytes. Inhibits thrombin-induced arachidonic acid release in platelets. Increases endothelial P-selectin expression via activation of protein kinase G. Used to study the activation of p38 mitogen-activated protein kinase by lipopolysaccharide in neutrophils.