Guanosine 5′-triphosphate lithium salt

• 产品号: G5884
• CAS号: 85737-04-8
• 分子式: C10H15LiN5O14P3
• 分子量: 529.113483
• 纯 度: ~95% (HPLC)

产品别名

• 标题: Guanosine 5′-triphosphate lithium salt
• IUPAC标准名: lithium(1+) ion 2-amino-9-[(2R,3R,4S,5R)-5-{[({[(hydrogen phosphonatooxy)(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl)oxy]methyl}-3,4-dihydroxyoxolan-2-yl]-6,9-dihydro-1H-purin-6-one
• IUPAC传统名: lithium(1+) ion 2-amino-9-[(2R,3R,4S,5R)-5-[({[hydrogen phosphonatooxy(hydroxy)phosphoryl]oxy(hydroxy)phosphoryl}oxy)methyl]-3,4-dihydroxyoxolan-2-yl]-1H-purin-6-one
• 别名: GTP lithium salt

产品登记号

• PubChem SID: 24895236
• MDL号: MFCD00070012
• CAS号: 85737-04-8

产品性质

• 纯度: ~95% (HPLC)
• 运输包装: dry ice
• 外观: white powder
• 溶解度: H2O: soluble100 mg/mL
• GHS警示词: Warning
• GHS危险声明: H315-H319-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• GHS警示性声明: P261-P305 + P351 + P338
• 危险公开号: 36/37/38
• 安全公开号: 22-26-36
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Caution
Stability is much better than sodium salt.
Preparation Note
Prepared by enzymatic phosphorylation of 5′-GMP.
Biochem/physiol Actions
GTP functions as a carrier of phosphates and pyrophosphates involved in channeling chemical energy into specific biosynthetic pathways. GTP activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of several intracellular kinase cascades. Proliferation and apoptosis are regulated in part by the hydrolysis of GTP by small GTPases Ras and Rho. Another type of small GTPase, Rab, plays a role in the docking and fusion of vesicles and may also be involved in vesicle formation. In addition to its role in signal transduction, GTP also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA.