Guanosine 3′,5′-cyclic monophosphate

• 产品号: G7504
• CAS号: 7665-99-8
• 分子式: C10H12N5O7P
• 分子量: 345.205341
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: Guanosine 3′,5′-cyclic monophosphate
• IUPAC标准名: 2-amino-9-{2,7-dihydroxy-2-oxo-hexahydro-1,3,5,2λ^5-furo[3,2-d][1,3,2λ^5]dioxaphosphinin-6-yl}-6,9-dihydro-3H-purin-6-one
• IUPAC传统名: cyclic guanosine monophosphate
• 别名: cGMP; cyclic GMP

产品登记号

• MDL号: MFCD00070129
• EC号: 231-641-6
• PubChem SID: 24895309
• CAS号: 7665-99-8

产品性质

• 纯度: ≥98% (HPLC)
• 外观: white powder
• 溶解度: 1% NaHCO3: soluble50 mg/mL
• GHS警示词: Warning
• GHS危险声明: H315-H319-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• GHS警示性声明: P261-P305 + P351 + P338
• 危险公开号: 36/37/38
• 安全公开号: 22-26-36
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
An important second messenger, cGMP is a major intracellular mediator of extracellular signals such as nitric oxide and natriuretic peptides. Cyclic GMP interacts with three types of intracellular receptor proteins: cGMP-dependent protein kinases, cGMP-regulated channels, and cGMP-regulated cyclic nucleotide phosphodiesterases. A primary action of elevated cGMP levels in vivo is the stimulation of cGMP-dependent protein kinase (PKG).
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. G7504.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.