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2-(Methylthio)adenosine 5′-diphosphate trisodium salt hydrate_分子结构_CAS_475193-31-8(anhydrous))
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2-(Methylthio)adenosine 5′-diphosphate trisodium salt hydrate

产品号 M152 公司名称 Sigma Aldrich
CAS号 475193-31-8(anhydrous) 公司网站 http://www.sigmaaldrich.com
分子式 C11H16N5Na3O11P2S 电 话 1-800-521-8956
分子量 557.253472 传 真
纯 度 ≥89% (HPLC) 电子邮件
保 存 desiccated Chembase数据库ID: 133570

产品价格信息

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产品别名

标题
2-(Methylthio)adenosine 5′-diphosphate trisodium salt hydrate
IUPAC标准名
trisodium hydrate [(2R,3S,4R,5R)-5-[6-amino-2-(methylsulfanyl)-9H-purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl (phosphonatooxy)phosphonate
IUPAC传统名
trisodium hydrate [(2R,3S,4R,5R)-5-[6-amino-2-(methylsulfanyl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl phosphonatooxyphosphonate
别名
2-Methylthio-ADP trisodium salt hydrate
2-(Methylthio)adenosine 5′-trihydrogen diphosphate trisodium salt hydrate

产品登记号

CAS号 475193-31-8(anhydrous)
PubChem SID 24278816
MDL号 MFCD11044463

产品性质

外观 white solid
溶解度 H2O: >20 mg/mL
个人保护装置 Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
保存条件 desiccated
保存温度 -20°C
德国WGK号 3
纯度 ≥89% (HPLC)

产品详细信息

详细说明 (English)
Caution
Hygroscopic, air sensitive
Biochem/physiol Actions
2-Methylthio-ADP (2-ME-SADP) is a P2 purinoceptor agonist, which induces platelet aggregation and shape change and inhibits cyclic AMP accumulation in platelets exposed to prostaglandin E1. Compared with ADP, 2-methylthio-ADP was 3-5 times as active as an aggregating agent and 150-200 times as active as an inhibitor of cyclic AMP accumulation. Purinergic signaling may be an important factor in TSP-1-mediated cell-matrix and cell-cell interactions such as those occurring during development and repair.

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