Bradykinin Fragment 1-5

• 产品号: B1401
• CAS号: 23815-89-6
• 分子式: C27H40N8O6
• 分子量: 572.6565
• 纯 度: ≥97% (HPLC)

产品别名

• 标题: Bradykinin Fragment 1-5
• IUPAC标准名: 2-[2-({1-[1-(2-amino-5-carbamimidamidopentanoyl)pyrrolidine-2-carbonyl]pyrrolidin-2-yl}formamido)acetamido]-3-phenylpropanoic acid
• IUPAC传统名: 2-[2-({1-[1-(2-amino-5-carbamimidamidopentanoyl)pyrrolidine-2-carbonyl]pyrrolidin-2-yl}formamido)acetamido]-3-phenylpropanoic acid

产品登记号

• PubChem SID: 24891591
• MDL号: MFCD00076260
• CAS号: 23815-89-6

产品性质

• 纯度: ≥97% (HPLC)
• 相关基因信息: human ... KNG1 (includes EG:3827)(3827)
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Amino Acid Sequence
Arg-Pro-Pro-Gly-Phe
Biochem/physiol Actions
The bradykinin (BK) fragment (1-5) (RPPGF) is among the most stable of naturally occurring metabolites. It may be used as a marker for BK production in vivo. It is known that an intact Arg residue in the C-terminus is required for biological activities. BK 1-5 is the minimal peptide that inhibited α-thrombin-induced platelet aggregation and secretion and calcium mobilization. It also prevented α-thrombin from cleaving the thrombin receptor peptide, NATLDPRSFLLR, between arginine and serine. Such antithrombin activities of BK 1-5 may contribute to the cardioprotective nature of kinins.