Piperacillin sodium salt

• 产品号: P8396
• CAS号: 59703-84-3
• 分子式: C23H26N5NaO7S
• 分子量: 539.53661

产品别名

• 标题: Piperacillin sodium salt
• IUPAC标准名: sodium (2S,5R,6R)-6-[(2R)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
• IUPAC传统名: sodium piperacillin(1-)

产品登记号

• MDL号: MFCD00917471
• EC号: 261-868-6
• CAS号: 59703-84-3
• Beilstein号: 5373920

产品性质

• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS编号: XI0180000
• 保存温度: 2-8°C
• 德国WGK号: 2

产品详细信息

详细说明 (English)

Application
Piperacillin is a semisynthetic, broad-spectrum ureidopenicillin antibiotic. It is derived from ampicillin. It has been used in pharmacokinetic studies in order to optimize antimicrobial therapy in patients with sepsis1. It is used to study piperacillin hypersensitivity reactions2 and to study multidrug-resistant organisms3.
Biochem/physiol Actions
Piperacillin inhibits the final stage of bacterial cell wall biosynthesis at the level of PBP binding.
Piperacillin inhibits the last stage of bacterial cell wall synthesis by binding to certain penicillin-binding proteins (PBPs), which results in cell lysis. Cell lysis is mediated by bacterial cell wall autolytic enzymes. Piperacillin may interfere with autolysin inhibitors.