Surfactin

• 产品号: S3523
• CAS号: 24730-31-2
• 分子式: C53H93N7O13
• 分子量: 1036.34462
• 纯 度: ≥98% (HPLC and TLC)

产品别名

• 标题: Surfactin
• IUPAC标准名: 3-[(2R,5S,8S,11R,14S,17S,20R,23S)-17-(carboxymethyl)-2-(11-methyldodecyl)-8,11,20,23-tetrakis(2-methylpropyl)-3,6,9,12,15,18,21,24-octaoxo-14-(propan-2-yl)-1-oxa-4,7,10,13,16,19,22-heptaazacyclotetracosan-5-yl]propanoic acid
• IUPAC传统名: 3-[(2R,5S,8S,11R,14S,17S,20R,23S)-17-(carboxymethyl)-14-isopropyl-2-(11-methyldodecyl)-8,11,20,23-tetrakis(2-methylpropyl)-3,6,9,12,15,18,21,24-octaoxo-1-oxa-4,7,10,13,16,19,22-heptaazacyclotetracosan-5-yl]propanoic acid

产品登记号

• PubChem SID: 24899562
• MDL号: MFCD00082048
• CAS号: 24730-31-2

产品性质

• 生物来源: from Bacillus subtilis
• 简要说明: zwitterionic
• 纯度: ≥98% (HPLC and TLC)
• 临界胶束浓度: 7.5-20 μmol/L (depending on methods)
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Application
Surfactin is used as a surfactant to mediate flux of mono-and divalent cations, such as calcium, across lipid bilayer membranes. It is also used to study antitumor activity, activity against enveloped viruses, activity against the protoplast of Bacillus megaterium and the activity against Mycoplasma1.
Biochem/physiol Actions
Surfactin is a lipopeptide antibiotic that is composed of one β-hydroxy fatty acid, which has a long fatty acid moiety, and seven amino acids. Three of them have D configurations. It is a powerful biosurfactant that causes lysis of erythrocytes and bacteria. It is also a clotting inhibitor. Surfactin is thought to disrupt or disintegrate membranes via physicochemical interaction with the membranes1.