您当前所在的位置:首页 > 产品中心 > 产品信息
土霉素 盐酸盐_分子结构_CAS_2058-46-0)
点击图片或这里关闭

土霉素 盐酸盐

产品号 O5875 公司名称 Sigma Aldrich
CAS号 2058-46-0 公司网站 http://www.sigmaaldrich.com
分子式 C22H25ClN2O9 电 话 1-800-521-8956
分子量 496.8949 传 真
纯 度 ≥95% (HPLC) 电子邮件
保 存 Chembase数据库ID: 133341

产品价格信息

请登录

产品别名

标题
Oxytetracycline hydrochloride
IUPAC标准名
(4S,4aR,5S,5aR,6S,12aS)-4-(dimethylamino)-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride
IUPAC传统名
oxytetracycline hydrochloride

产品登记号

MDL号 MFCD00135815
PubChem SID 24898027
Beilstein号 3853107
CAS号 2058-46-0
EC号 218-161-2

产品性质

纯度 ≥95% (HPLC)
适用性 suitable for 1694 per US EPA
外观 yellow crystalline
个人保护装置 Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RTECS编号 QI8225000
德国WGK号 2

产品详细信息

详细说明 (English)
Application
Oxytetracycline is a tetracycline analog isolated from the actinomycete streptomyces rimosus. Oxytetracycline is an antibiotic indicated for treatment of infections caused by Gram positive and Gram negative microorganisms such as Mycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae, and Diplococcus pneumoniae. It is used in studies on the oxytetracycline-resistance gene (otrA). Oxytetracycline hydrochloride is used to study phagosome-lysosome (P-L) fusion in P388D1 cells1 and antibiotic susceptibilities of Mycopasma bovis isolates2. Product O5875 is ≥95% (HPLC), crystalline.
Biochem/physiol Actions
Oxytetracycline inhibits translation which results in cell death. It binds to the 30S ribosomal subunit and prevents the amino-acyl tRNA from binding to the A site of the ribosome. The binding is reversible in nature. Oxytetracycline is lipophilic so it can easily pass through a cell membrane and passively diffuses through channels in the bacterial membrane.

参考文献