1-Deoxymannojirimycin hydrochloride

• 产品号: D9160
• CAS号: 73465-43-7
• 分子式: C6H14ClNO4
• 分子量: 199.63266

产品别名

• 标题: 1-Deoxymannojirimycin hydrochloride
• IUPAC标准名: (2R,3R,4R,5R)-2-(hydroxymethyl)piperidine-3,4,5-triol hydrochloride
• IUPAC传统名: deoxymannojirimycin hydrochloride
• 别名: 1,5-Dideoxy-1,5-imino-D-mannitol hydrochloride

产品登记号

• MDL号: MFCD00083611
• PubChem SID: 24894265
• CAS号: 73465-43-7

产品性质

• GHS警示词: Warning
• GHS危险声明: H302-H312-H332
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• GHS警示性声明: P280
• 危险公开号: 20/21/22
• 安全公开号: 36
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Application
1-Deoxymannojirimycin (DMM) hydrochloride is an inhibitor of N-linked glycosylationan and has antiviral activity. Derivatives of deoxymannojirimycin may have anti-HIV activity. It has been used for treatment of T lymphocytes and to study it′s effect on allogeneic cytotoxic T lymphocytes (CTL)1. It is used for studies on Golgi-mediated glycoprotein processing.
Biochem/physiol Actions
1-Deoxymannojirimycin is an inhibitor of N-linked glycosylation. It is a mannosidase I inhibitor, alters cell-surface complex carbohydrate structure as assayed by PHA-L binding, and increases high mannose structures as indicated by the increased Con-A binding1.