Spironolactone

• 产品号: S3378
• CAS号: 52-01-7
• 分子式: C24H32O4S
• 分子量: 416.57348
• 纯 度: 97.0-103.0%

产品别名

• 标题: Spironolactone
• IUPAC标准名: (1'S,2R,2'R,9'R,10'R,11'S,15'S)-9'-(acetylsulfanyl)-2',15'-dimethylspiro[oxolane-2,14'-tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecan]-6'-ene-5,5'-dione
• IUPAC传统名: spironolactone
• 别名: 4-Pregnen-21-oic acid-17α-ol-3-one-7α-thiol γ-lactone 7-acetate; 7α-(Acetylthio)-17α-hydroxy-3-oxopregn-4-ene-21-carboxylic acid γ-lactone

产品登记号

• EC号: 200-133-6
• PubChem SID: 24277736
• CAS号: 52-01-7
• MDL号: MFCD00082250

产品性质

• 纯度: 97.0-103.0%
• 相关基因信息: human ... HSD17B1(3292), NR3C2(4306)rat ... Ar(24208)
• 熔点: 207-208 °C(lit.)
• GHS警示词: Danger
• GHS危险声明: H360
• 欧盟危险性物质标志: 有毒(Toxic) (T)
• 个人保护装置: Eyeshields, Gloves, type P2 (EN 143) respirator cartridges
• GHS警示性声明: P201-P308 + P313
• 危险公开号: 60
• 安全公开号: 53-22-36/37/39-45
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Spironolactone is a competitive aldosterone receptor antagonist. Used as potassium sparing diuretic.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. S3378.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.