Biochem/physiol Actions Blocks the LPS- or cytokine-induced activation of nuclear factor κB (NF-κB), which, in turn, blocks the induction of iNOS and COX-2 transcription. Blocks activation of pp70s6k by all mitogens. Blocks apoptosis in cell lines by inhibiting the processing of caspases in some cell lines and to some stimuli. Caution Stable at least two years when stored desiccated at -20°C. |