5-(N,N-二甲基)阿米洛利 盐酸盐

• 产品号: A4562
• CAS号: 1214-79-5
• 分子式: C8H13Cl2N7O
• 分子量: 294.14112

产品别名

• 标题: 5-(N,N-Dimethyl)amiloride hydrochloride
• IUPAC标准名: 3-amino-6-chloro-N-(diaminomethylidene)-5-(dimethylamino)pyrazine-2-carboxamide hydrochloride
• IUPAC传统名: 3-amino-6-chloro-N-(diaminomethylidene)-5-(dimethylamino)pyrazine-2-carboxamide hydrochloride
• 别名: 3-氨基-N-(氨基亚氨基乙基)-5-(二甲氨基)-6-氯吡嗪甲酰胺 盐酸盐; DMA

产品登记号

• MDL号: MFCD00069207
• CAS号: 1214-79-5
• PubChem SID: 24278216

产品性质

• 相关基因信息: human ... SCNN1A(6337), SCNN1B(6338), SCNN1D(6339), SCNN1G(6340), SLC9A1(6548)mouse ... Scnn1a(20276), Scnn1b(20277), Scnn1d(140501), Scnn1g(20278)rat ... Scnn1a(25122), Scnn1b(24767), Scnn1g(24768), Slc9a1(24782), Slc9a2(24783), Slc9a3(24784)
• GHS警示词: Warning
• GHS危险声明: H315-H319-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• GHS警示性声明: P261-P305 + P351 + P338
• 危险公开号: 36/37/38
• 安全公开号: 26
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Selective blocker of Na+/H+ antiport; IC50 = 6.9 μM.
Application
5-(N,N-Dimethyl)amiloride hydrochloride is a selective blocker of Na2/H+ antiport. 5-(N,N-Dimethyl)amiloride hydrochloride has been investigated for its ability to reduce inflammatory pain.