5-Iodotubericidin

• 产品号: I100
• CAS号: 24386-93-4
• 分子式: C11H13IN4O4
• 分子量: 392.14979
• 纯 度: ≥90%

产品别名

• 标题: 5-Iodotubericidin
• IUPAC标准名: (2R,3R,4S,5R)-2-{4-amino-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl}-5-(hydroxymethyl)oxolane-3,4-diol
• IUPAC传统名: 5-iodotubercidin
• 别名: 5-Iodotubericidin; 4-Amino-5-iodo-7-(β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine; 7-Iodo-7-deazaadenosine

产品登记号

• MDL号: MFCD00055131
• CAS号: 24386-93-4

产品性质

• 纯度: ≥90%
• 外观: tan solid
• 溶解度: 0.1 M HCl: soluble0.7 mg/mL
• 溶解度: 0.1 M NaOH: soluble0.8 mg/mL
• 溶解度: DMSO: soluble36 mg/mL
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
5-Iodotubercidin increases fatty acid oxidation activity and glycogen synthesis in hepatocytes. 5-Iodotubercidin is also a potent inhibitor of adenosine uptake into brain.
Potent inhibitor of adenosine uptake into brain, and of adenosine kinase and subsequent metabolism of adenine nucleotides. In cultured rat hepatocytes, 5-iodotubercidin inhibits both acetyl-CoA carboxylase and de novo synthesis of fatty acids and cholesterol.1
Caution
Solutions may be stored frozen. Use promptly when thawed and protect from exposure to light.