S(+)-Niguldipine hydrochloride

• 产品号: N135
• CAS号: 113165-32-5
• 分子式: C36H40ClN3O6
• 分子量: 646.1723

产品别名

• 标题: S(+)-Niguldipine hydrochloride
• IUPAC标准名: 3-[3-(4,4-diphenylpiperidin-1-yl)propyl] 5-methyl (4S)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride
• IUPAC传统名: 3-[3-(4,4-diphenylpiperidin-1-yl)propyl] 5-methyl (4S)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride
• 别名: S(+)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-(4,4-diphenyl-1-piperidinyl)-propyl methyl ester hydrochloride

产品登记号

• CAS号: 113165-32-5
• MDL号: MFCD00873564
• PubChem SID: 24897482

产品性质

• 外观: yellow solid
• 比旋光度: [α]22/D +14.62°, c = 0.13 in methanol(lit.)
• 溶解度: DMSO: soluble13 mg/mL
• 溶解度: ethanol: soluble16 mg/mL
• 溶解度: methanol: soluble8 mg/mL
• 溶解度: H2O: insoluble
• 溶解度: dilute aqueous acid: insoluble
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Caution
Photosensitive. This compound adsorbs strongly to plastic.
Biochem/physiol Actions
α1A-adrenoceptor antagonist; antihypertensive agent; L-type Ca2+ channel blocker; potassium agonist that activates Ca2+-activated maxi K-channels.