潮霉素 B 来源于吸水链霉菌

• 产品号: H3274
• CAS号: 31282-04-9
• 分子式: C20H37N3O13
• 分子量: 527.52008
• 纯 度: ≥60% (HPAE)

产品别名

• 标题: Hygromycin B from Streptomyces hygroscopicus
• IUPAC标准名: (2S,3'R,3aS,4S,4'S,5'R,6R,6'R,7S,7aS)-4-{[(1R,2S,3R,5S,6R)-3-amino-2,6-dihydroxy-5-(methylamino)cyclohexyl]oxy}-6'-[(1R)-1-amino-2-hydroxyethyl]-6-(hydroxymethyl)-tetrahydro-3aH-spiro[[1,3]dioxolo[4,5-c]pyran-2,2'-oxane]-3',4',5',7-tetrol
• IUPAC传统名: (2S,3'R,3aS,4S,4'S,5'R,6R,6'R,7S,7aS)-4-{[(1R,2S,3R,5S,6R)-3-amino-2,6-dihydroxy-5-(methylamino)cyclohexyl]oxy}-6'-[(1R)-1-amino-2-hydroxyethyl]-6-(hydroxymethyl)-tetrahydro-3aH-spiro[[1,3]dioxolo[4,5-c]pyran-2,2'-oxane]-3',4',5',7-tetrol

产品登记号

• PubChem SID: 24895568
• MDL号: MFCD06795479
• CAS号: 31282-04-9
• EC号: 250-545-5

产品性质

• 适用性: suitable for cell culture
• 适用性: suitable for insect cell culture
• 纯度: ≥60% (HPAE)
• 外观: powder
• 溶解度: H2O: soluble50 mg/mL (As a stock solution. Stock solutions should be stored at 2-8°C. Stable at 37°C for 30 days.)
• GHS警示词: Danger
• GHS危险声明: H300 +H310 + H330-H318-H334
• 欧盟危险性物质标志: 剧毒(Highly toxic) (T+)
• GHS警示性声明: P260-P264-P280-P284-P301 + P310-P302 + P350
• RID/ADR: UN 3462 6.1/PG 1
• 危险公开号: 26/27/28-41-42/43
• RTECS编号: WK2130000
• 安全公开号: 22-26-28-36/37/39-45
• 保存温度: 2-8°C
• 联合国危险货物等级: 6.1
• 联合国危险货物编号: 3462
• 联合国危险货物包装类别(PG): 1
• 德国WGK号: 3

产品详细信息

详细说明 (简体中文)

Biochem/physiol Actions
Mode of Action: Blocks polypeptide synthesis and inhibits elongation. For use in the selection and maintenance of prokaryotic and eukaryotic cells.
Preparation Note
通过离子交换色谱纯化
Application
Use to study protein synthesis at the level of 70S ribosome translocation and mRNA template misreading. Use as a selection agent for hygromycin resistance gene transformed cells. Recommended for use as a selection agent at 100-800 μg/mL.
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information