潮霉素 B 来源于吸水链霉菌

• 产品号: H7772
• CAS号: 31282-04-9
• 分子式: C20H37N3O13
• 分子量: 527.52008

产品别名

• 标题: Hygromycin B from Streptomyces hygroscopicus
• IUPAC标准名: (2S,3'R,3aS,4S,4'S,5'R,6R,6'R,7S,7aS)-4-{[(1R,2S,3R,5S,6R)-3-amino-2,6-dihydroxy-5-(methylamino)cyclohexyl]oxy}-6'-[(1R)-1-amino-2-hydroxyethyl]-6-(hydroxymethyl)-tetrahydro-3aH-spiro[[1,3]dioxolo[4,5-c]pyran-2,2'-oxane]-3',4',5',7-tetrol
• IUPAC传统名: (2S,3'R,3aS,4S,4'S,5'R,6R,6'R,7S,7aS)-4-{[(1R,2S,3R,5S,6R)-3-amino-2,6-dihydroxy-5-(methylamino)cyclohexyl]oxy}-6'-[(1R)-1-amino-2-hydroxyethyl]-6-(hydroxymethyl)-tetrahydro-3aH-spiro[[1,3]dioxolo[4,5-c]pyran-2,2'-oxane]-3',4',5',7-tetrol

产品登记号

• MDL号: MFCD06795479
• PubChem SID: 24895807
• CAS号: 31282-04-9
• EC号: 250-545-5

产品性质

• 提纯方法: ion-exchange chromatography
• 外观: lyophilized powder
• GHS警示词: Danger
• GHS危险声明: H300 +H310 + H330-H318-H334
• 欧盟危险性物质标志: 剧毒(Highly toxic) (T+)
• GHS警示性声明: P260-P264-P280-P284-P301 + P310-P302 + P350
• RID/ADR: UN 3462 6.1/PG 1
• 危险公开号: 26/27/28-41-42/43
• RTECS编号: WK2130000
• 安全公开号: 22-26-28-36/37/39-45
• 保存温度: 2-8°C
• 联合国危险货物等级: 6.1
• 联合国危险货物编号: 3462
• 联合国危险货物包装类别(PG): 1
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Mode of Action: Blocks polypeptide synthesis and inhibits elongation. For use in the selection and maintenance of prokaryotic and eukaryotic cells.
Application
Hygromycin B is an aminoglycoside antibiotic produced by the bacterium Streptomyces hygroscopicus that kills bacteria, fungi and higher eukaryotic cells by inhibiting protein synthesis. It is used for the selection and maintenance of prokaryotic and eukaryotic cells that contain the hygromycin resistance gene. It is used in gene transfer experiments as a selection agent1,2,3.
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information