Veratridine

• 产品号: V5754
• CAS号: 71-62-5
• 分子式: C36H51NO11
• 分子量: 673.79024
• 纯 度: ≥90% (HPLC)

产品别名

• 标题: Veratridine
• IUPAC标准名: (1R,10R,11S,12S,14R,19S,23R,25R)-1,10,11,12,14,23-hexahydroxy-6,10,19-trimethyl-24-oxa-4-azaheptacyclo[12.12.0.0^2,^1^1.0^4,^9.0^1^5,^2^5.0^1^8,^2^3.0^1^9,^2^5]hexacosan-22-yl 3,4-dimethoxybenzoate
• IUPAC传统名: (1R,10R,11S,12S,14R,19S,23R,25R)-1,10,11,12,14,23-hexahydroxy-6,10,19-trimethyl-24-oxa-4-azaheptacyclo[12.12.0.0^2,^1^1.0^4,^9.0^1^5,^2^5.0^1^8,^2^3.0^1^9,^2^5]hexacosan-22-yl 3,4-dimethoxybenzoate
• 别名: 3-Veratroylveracevine

产品登记号

• CAS号: 71-62-5
• MDL号: MFCD00082515
• Beilstein号: 78875
• EC号: 200-758-4
• PubChem SID: 24900756

产品性质

• 纯度: ≥90% (HPLC)
• 外观: white to off-white powder
• 溶解度: ethanol: soluble50 mg/mL
• GHS警示词: Danger
• GHS危险声明: H300-H310-H315-H319-H330-H335-H361-H373-H412
• 欧盟危险性物质标志: 剧毒(Highly toxic) (T+)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• GHS警示性声明: P260-P264-P273-P280-P284-P301 + P310
• RID/ADR: UN 1544 6.1/PG 1
• 危险公开号: 26/27/28-36/37/38-48/20-52/53-62
• RTECS编号: YX5600000
• 安全公开号: 26-28-36/37-45-61
• 保存温度: -20°C
• 联合国危险货物等级: 6.1
• 联合国危险货物编号: 1544
• 联合国危险货物包装类别(PG): 1
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Opens voltage-dependent Na+ channels and prevents their inactivation. This, in turn, opens voltage-activated calcium channels, thus increasing intracellular calcium content and inducing neurotransmitter release. Alkaloid neurotoxin which depolarizes excitable tissue; used to increase membrane sodium permeability. Veratridine is cytotoxic to chromaffin cells in vitro.