S-15176 difumarate salt

• 产品号: S5944
• CAS号: 148913-55-7
• 分子式: C39H56N2O12S
• 分子量: 776.93314
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: S-15176 difumarate salt
• IUPAC标准名: bis((2E)-but-2-enedioic acid); 2,6-di-tert-butyl-4-[(3-{4-[(3,4,5-trimethoxyphenyl)methyl]piperazin-1-yl}propyl)sulfanyl]phenol
• IUPAC传统名: 2,6-di-tert-butyl-4-[(3-{4-[(3,4,5-trimethoxyphenyl)methyl]piperazin-1-yl}propyl)sulfanyl]phenol; bis(fumaric acid)
• 别名: N-[(3,5-Di-tert-butyl-4-hydroxy-1-thiophenyl)]-3-propyl-N′-(2,3,4-trimethoxybenzyl)piperazine difumarate salt

产品登记号

• CAS号: 148913-55-7
• MDL号: MFCD11046049

产品性质

• 纯度: ≥98% (HPLC)
• 外观: solid
• 溶解度: DMSO: soluble16 mg/mL
• 溶解度: H2O: insoluble
• GHS警示词: Warning
• GHS危险声明: H315-H319-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• GHS警示性声明: P261-P305 + P351 + P338
• 危险公开号: 36/37/38
• 安全公开号: 26-36
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Antioxidant and anti-ischemic agent. Also inhibits mitochondrial permeability transition, prevents the early step in apoptosis by preventing collapse of the electrochemical gradient across the mitochondrial membrane. IC50 for in vitro lipid peroxidation is 0.3 μM. IC50 for carnitine palmitoyltransferase (CPT-1) in heart homogenate is 16.8 μM. The shift from fatty acid to glucose oxidation may contribute to anti-ischemic effect.