5-(N-Methyl-N-isobutyl)-amiloride

• 产品号: A5585
• CAS号: 96861-65-3
• 分子式: C11H18ClN7O
• 分子量: 299.75992
• 纯 度: ≥98% (TLC)

产品别名

• 标题: 5-(N-Methyl-N-isobutyl)-amiloride
• IUPAC标准名: 3-amino-N-carbamimidoyl-6-chloro-5-[methyl(2-methylpropyl)amino]pyrazine-2-carboxamide
• IUPAC传统名: 3-amino-N-carbamimidoyl-6-chloro-5-[methyl(2-methylpropyl)amino]pyrazine-2-carboxamide
• 别名: MIA

产品登记号

• PubChem SID: 24278228
• MDL号: MFCD00078567
• CAS号: 96861-65-3

产品性质

• 纯度: ≥98% (TLC)
• 相关基因信息: human ... SCNN1A(6337), SCNN1B(6338), SCNN1D(6339), SCNN1G(6340)mouse ... Scnn1a(20276), Scnn1b(20277), Scnn1d(140501), Scnn1g(20278)rat ... Scnn1a(25122), Scnn1b(24767), Scnn1g(24768)
• 外观: powder
• GHS警示词: Warning
• GHS危险声明: H315-H319-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• GHS警示性声明: P261-P305 + P351 + P338
• 危险公开号: 36/37/38
• 安全公开号: 26-36
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Potent blocker of the Na+/H+ antiport. Possible antitumor agent.
Application
5-(N-Methyl-N-isobutyl)-amiloride is a potent blocker of the Na2/H+ antiport. 5-(N-Methyl-N-isobutyl)-amiloride has been used to study early cellular response to acidosis.