Atrial Natriuretic Peptide human

• 产品号: A1663
• CAS号: 91917-63-4
• 分子式: C127H205N45O39S3
• 分子量: 3082.4597
• 纯 度: ≥97% (HPLC)

产品别名

• 标题: Atrial Natriuretic Peptide human
• IUPAC标准名: 3-{2-[2-(2-{2-[2-(2-{2-[2-(2-{2-[2-(2-amino-3-hydroxypropanamido)-4-methylpentanamido]-5-carbamimidamidopentanamido}-5-carbamimidamidopentanamido)-3-hydroxypropanamido]-3-hydroxypropanamido}-3-sulfanylpropanamido)-3-phenylpropanamido]acetamido}acetamido)-5-carbamimidamidopentanamido]-4-(methylsulfanyl)butanamido}-3-({4-carbamimidamido-1-[(1-{[({1-[(1-{[1-({[(1-{[({1-[(1-{[1-({1-[(4-carbamimidamido-1-{[1-carboxy-2-(4-hydroxyphenyl)ethyl]carbamoyl}butyl)carbamoyl]-2-phenylethyl}carbamoyl)-2-hydroxyethyl]carbamoyl}-2-carbamoylethyl)carbamoyl]-2-sulfanylethyl}carbamoyl)methyl]carbamoyl}-3-methylbutyl)carbamoyl]methyl}carbamoyl)-2-hydroxyethyl]carbamoyl}-3-carbamoylpropyl)carbamoyl]ethyl}carbamoyl)methyl]carbamoyl}-2-methylbutyl)carbamoyl]butyl}carbamoyl)propanoic acid
• IUPAC传统名: 3-{2-[2-(2-{2-[2-(2-{2-[2-(2-{2-[2-(2-amino-3-hydroxypropanamido)-4-methylpentanamido]-5-carbamimidamidopentanamido}-5-carbamimidamidopentanamido)-3-hydroxypropanamido]-3-hydroxypropanamido}-3-sulfanylpropanamido)-3-phenylpropanamido]acetamido}acetamido)-5-carbamimidamidopentanamido]-4-(methylsulfanyl)butanamido}-3-({4-carbamimidamido-1-[(1-{[({1-[(1-{[1-({[(1-{[({1-[(1-{[1-({1-[(4-carbamimidamido-1-{[1-carboxy-2-(4-hydroxyphenyl)ethyl]carbamoyl}butyl)carbamoyl]-2-phenylethyl}carbamoyl)-2-hydroxyethyl]carbamoyl}-2-carbamoylethyl)carbamoyl]-2-sulfanylethyl}carbamoyl)methyl]carbamoyl}-3-methylbutyl)carbamoyl]methyl}carbamoyl)-2-hydroxyethyl]carbamoyl}-3-carbamoylpropyl)carbamoyl]ethyl}carbamoyl)methyl]carbamoyl}-2-methylbutyl)carbamoyl]butyl}carbamoyl)propanoic acid
• 别名: hANF; ANF 1-28

产品登记号

• CAS号: 91917-63-4
• PubChem SID: 24890580
• MDL号: MFCD00076226

产品性质

• 纯度: ≥97% (HPLC)
• 相关基因信息: human ... NPPA(4878)
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Amino Acid Sequence
Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr [Disulfide bridge: 7-23]
Biochem/physiol Actions
Atrial natriuretic peptide (ANP) is synthesized in myoendocrine cells of the heart from which it is released into the circulation. It exerts natriuretic, diuretic, and vasodilatory effects through stimulation of guanylate cyclase-linked NPR-A receptors. It plays an important role in blood volume and blood pressure homeostasis.